irreversible

Definition

Incapable of being reversed or turned about or back; incapable of being made to run backwards.

Etymology

From ir- + reversible.

Example Sentences

• "an irreversible engine"
• "an irreversible sentence or decree"
• "Manganism has been known about since the 19th century, when miners exposed to ores containing manganese[…]began to totter, slur their speech and behave like someone inebriated. The poisoning was irreversible, and soon ended in psychosis and death."