apoptosis

Definition

A process of programmed cell death by which cells undergo an ordered sequence of events which leads to death of the cell, as occurs during growth and development of the organism, as a part of normal cell aging, or as a response to cellular injury.

Etymology

From Ancient Greek ἀπόπτωσις (apóptōsis, “a falling off”), from ἀπό (apó, “away from”) + πτῶσις (ptôsis, “falling”).

Example Sentences

• "The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations."
• "Indeed, so important is apoptosis that it is gradually becoming clear that almost all therapeutic cancer treatment works only because it induces apoptosis by alerting p53 and its colleagues."
• "Apoptosis is routine in developmental processes such as the removal of webbing between fingers in humans, the loss of tadpole tails in amphibians, and insect metamorphosis."